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Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study

Identifieur interne : 004300 ( Main/Exploration ); précédent : 004299; suivant : 004301

Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study

Auteurs : H. Shyla Jebashree [Inde] ; S. Jayasurya Kingsley [Inde] ; Emmanuel S. Sathish [Inde] ; D. Devapriya [Inde]

Source :

RBID : PMC:3169913

Abstract

Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of P. guajavashowed activity against both S. mutans and C. albicans. Maximum zone of inhibition was observed in ethyl acetate of P. guajava. The four extracts of T. chebula and M. elengi showed antibacterial activity against S. mutans. M. elengi extracts and ethanol extract of T. chebula did not show any antifungal activity against C. albicans. Except for the hexane extract of A. aspera, the other three extracts showed activity against the tested microbes. The ethyl acetate P. guajava leaf extract showed the minimum inhibitory concentration (MIC) against S. mutans to be <0.076 mg/mL in both MHB and BHI. The P. guajava ethyl acetate extract was subjected to GC-MS.


Url:
DOI: 10.5402/2011/541421
PubMed: 21991479
PubMed Central: 3169913


Affiliations:


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<p>Hexane, ethyl acetate, ethanol and methanol extracts of
<italic>Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera</italic>
were tested against the dental caries causing bacteria
<italic>Streptococcus mutans</italic>
and fungus
<italic>Candida albicans</italic>
isolated from caries infected patients. All the four extracts of
<italic>P. guajava</italic>
showed activity against both
<italic>S. mutans</italic>
and
<italic>C. albicans</italic>
. Maximum zone of inhibition was observed in ethyl acetate of
<italic>P. guajava</italic>
. The four extracts of
<italic>T. chebula</italic>
and
<italic>M. elengi</italic>
showed antibacterial activity against
<italic>S. mutans</italic>
.
<italic>M. elengi</italic>
extracts and ethanol extract of
<italic>T. chebula</italic>
did not show any antifungal activity against
<italic>C. albicans</italic>
. Except for the hexane extract of
<italic>A. aspera</italic>
, the other three extracts showed activity against the tested microbes. The ethyl acetate
<italic>P. guajava</italic>
leaf extract showed the minimum inhibitory concentration (MIC) against
<italic>S. mutans</italic>
to be <0.076 mg/mL in both MHB and BHI. The
<italic>P. guajava</italic>
ethyl acetate extract was subjected to GC-MS.</p>
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   |area=    EdenteV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:3169913
   |texte=   Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study
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Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:21991479" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a EdenteV2 

Wicri

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